LSP KIF5B 5 FISH Probe

The KIF5B 5’ FISH Probe is designed to detect the human KIF5B gene 5’-region located on chromosome band 10p11.22. KIF5B is also known as KNS, KINH, KNS1, UKHC or HEL-S-61.

The KIF5B 5 FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.

The KIF5B 5 FISH probe hybridizes to chromosome 10 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 10p11.22 region on the chromosome 10. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 10p11.22. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 10.

For Research Use Only.