LSP ETV6 3 FISH Probe

The ETV6 3’ FISH Probe is designed to detect the human ETV6 gene 3’-region located on chromosome band 12p13.2. ETV6 is also known as TEL or TEL1.

The ETV6 3 FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with the appropriate filters.

The ETV6 3 FISH probe hybridizes to chromosome 12 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 12p13.2 region on the chromosome 12. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 12p13.2. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 12.

For Research Use Only.